Functional GI Disorders
Chronic constipation, functional diarrhea, bloating, SIBO — conditions where intestinal function is impaired without visible structural changes. FMT is being studied as a way to restore normal GI function.
What are functional disorders?
A group of conditions in which intestinal function is impaired, but examination reveals no inflammation or structural changes.
Conditions included
- Chronic constipation
Infrequent or difficult bowel movements
- Functional diarrhea
Frequent loose stools without IBD
- Functional bloating
Chronic bloating and discomfort
- SIBO
Small Intestinal Bacterial Overgrowth
Common symptoms
- Altered stool frequency and consistency
- Abdominal bloating and excessive gas
- Abdominal discomfort or pain
- Impaired digestion and absorption
The role of the microbiome
- The microbiome regulates gut motility
- Bacteria produce gases and metabolites
- Imbalance is linked to constipation and diarrhea
- SIBO is a direct consequence of microbiota disruption
Conventional treatment
Laxatives, antidiarrheals, probiotics, diet — often provide only temporary relief.
Many patients spend years searching for an effective solution, switching from one medication to another without lasting results.
Why FMT?
In functional disorders, the microbiome plays a key role. FMT can help restore normal intestinal function.
Microbiota imbalance
Reduced beneficial bacteria, overgrowth of pathogens
Functional impairment
Slowed/accelerated transit, gas production
FMT transplantation
Restoration of a healthy ecosystem
Normalization
Restored normal transit and function
Mechanism of action
Healthy microbiota normalizes peristalsis, reduces excessive gas production, improves bile acid metabolism, and restores barrier function.
Potential benefits
- Targets the cause, not just symptoms
- Comprehensive improvement of GI function
- Potential for long-lasting effect
- Minimal side effects
Current state of research
FMT for functional disorders is a promising field with a growing evidence base.
70.3%
Constipation: 8,258 patients, 3 months
8,258
Largest group in the Han's United cohort
15,000+
Total Han's United patient cohort
↑
Growing scientific interest
Research directions
- Han's United — chronic constipation: 8,258 patients — the largest group in the cohort. 70.3% clinical improvement at 3 months
- Chronic diarrhea (dysbiosis): FMT restores normal microbiota balance, normalizing stool patterns
- SIBO and functional bloating: Restoration of normal bacterial balance, reduction of gas production
Free consultation · We respond within 24 hours
Patient story
Experience of treating chronic constipation with FMT
"Chronic constipation had plagued me for over 15 years. Laxatives stopped working, diets were ineffective. At Han's United, I was prescribed a course of FMT. My bowels started working on their own — for the first time in years. Bloating is almost gone, and I've stopped depending on medications."
Chen L.
48 years old, Nanchang
* Name changed. Results are individual and may vary.
Related conditions
FMT is also being studied for other GI conditions
Ulcerative Colitis
510 Han's United patients, 64.3% improvement at 3 months. Active clinical trials.
Crohn's Disease
Inflammatory bowel disease. Part of the IBD cohort (510 Han's United patients).
IBS
1,940 Han's United patients, 70.6% improvement at 3 months.
Chronic Diarrhea
1,730 Han's United patients, 81.0% improvement at 3 months and 72.3% at 3 years.
Related Articles
Looking for a solution?
If functional GI disorders are affecting your quality of life, schedule a consultation. A doctor will assess whether FMT could help in your case.
Free consultation · We respond within 24 hours
China, Jiangxi Province, Shangrao City, Guangxin District, West Binjiang Road