One source
All ten stories come from Jialan clinic materials supplied for the project's knowledge base.
Patient stories and clinical cases
10 cases from clinic materials, with context and limitations
We have included all ten cases available in the knowledge base: baseline, treatment format, timeline, and changes noted by patients, families, or teachers.
These are individual case descriptions, not proof that a method is effective. One person's outcome cannot predict another's.
Case file
What we are publishing
03Three cases in detail
07Seven more cases
Data source
What we are publishing
This section is based on Jialan clinic presentation materials and the parent messages included in them. The localized page text omits names; the unchanged original panels may contain pseudonyms, photographs, chats and documents from the partner's material.
Originals with context
Names are omitted from the page text. Full photographs and chat screenshots appear only inside the partner's original panels; children's faces were masked in the source.
No extra conclusions
Family observations are separated from objective data, and limitations appear beside every case.
Collection overview
What the ten cases contain
Categories reflect the main situation under which each case is described in the source materials.
10
cases in total
Three are shown in detail and seven in a compact format.
7
autism cases
One of these also mentions attention deficit hyperactivity disorder.
2
ADHD cases
ADHD is the main situation in two stories.
1
adult case
An 82-year-old man with depression and gastrointestinal complaints.
03 / 10
Three cases in detail
For these stories, the source materials provide enough detail to show baseline, course sequence, and the changes that were noted.
Show cases
10
02
Autism · child
Boy, age 5: constipation and a highly restricted diet
The materials list autism, severe constipation, a restricted diet, and difficulty with social interaction.
Baseline
- Before the course, bowel movements occurred once every 5–7 days and were dry and hard.
- The child accepted only a small range of foods.
- Communication and interaction difficulties were described.
Course timeline
3 July 2022
A gut microbiota test was performed.
13 July 2022
The materials record an FMT procedure.
13 August 2022
A follow-up microbiota test was performed.
Changes noted afterward
- The family noted a bowel movement every one to two days.
- The range of accepted foods expanded.
- More active social interaction was noted.
Source: Jialan clinic presentation with test dates and a description of the family's observations.
Limitation: There are no standardized symptom scales, control group, or details of other interventions; the course cannot be proven to have caused the changes.
Below is the partner's original material in Chinese. Claims inside the image have not been independently verified and do not prove treatment effectiveness.
Translated material
A case of autism
Liu so-and-so, a boy of five full years. When the child was a little over two, his speech development fell behind, he made no eye contact, liked to play alone, did not communicate with people, often talked to himself and had no spontaneous speech. At three and a half he was diagnosed with childhood autism. At the same time the child had severe constipation: a bowel movement once every 5–7 days, dry and hard, like goat droppings; he was also severely selective about food. On 3 July 2022 the child had a gut microbiota test, which found that he had far fewer species of gut bacteria than his peers.
On 13 July 2022 the child underwent gut microbiota transplantation. On 13 August 2022 a repeat microbiota test showed marked improvement. The child's parents were also followed up: he now has a bowel movement every one to two days, formed, and his food selectivity has improved greatly. Most gratifying of all, the child has begun to approach people on his own and lets peers at kindergarten hold on to his clothes and play with him.
08
ADHD · child
Girl, age 4: attention, behavior, and dry stool
The source materials list ADHD, difficulty concentrating, and dry stool; the baseline microbiota score was 46.
Baseline
- A short attention span and difficulty following instructions were described.
- The parent noted impulsive behavior.
- Dry stool was also mentioned.
Course timeline
27 May–1 June
First six-day course: eight capsules per day.
27 June–2 July
Second six-day course at the same stated dose.
After the courses
The materials include observations from the parent and teacher.
Changes noted afterward
- The parent reported bowel movements once or twice a day, easier defecation, and better sleep and eating.
- According to the parent, the child could stay through a 45-minute session instead of roughly ten minutes.
- The teacher reported better instruction-following, steadier emotions and more imitation of actions and sounds; the message states that about 70% of the set goals had been met.
- The material also shows that the child began eating vegetables she had previously avoided.
Source: Jialan clinic presentation and the parent and teacher messages included in it.
Limitation: Observers described the changes without a standardized repeat ADHD assessment; a causal link to the course cannot be established.
Below is the partner's original material in Chinese. Claims inside the image have not been independently verified and do not prove treatment effectiveness.
Translated material
Case: ADHD
- Nickname
- Domi
- Sex
- female
- Age
- 4 years
- Main problems
- attention deficit disorder, does not follow instructions, unfocused gaze, dry stool
Overall gut score: 46
The infographic marks this as "moderate imbalance". The section of the slide is titled "1. Overall health of the gut microbiota".
Table of indicators: name, assessed value, result
| Gut microbiota status | −1.39 |
|---|---|
| Microbiota colonization resistance | 1.5361 — normal |
| Gut metabolic capacity assessment | 54 |
| Gut synthetic capacity assessment | 47 |
| Microbiota diversity | 5.12 — normal |
| Number of gut microorganism species | 1039 — normal |
| Enterotype | I |
| Firmicutes / Bacteroidetes (F/B) | 0.7466 |
| Beneficial bacteria | — |
| Harmful bacteria | — |
The coloured result labels next to these rows are too small on the panel to read reliably: [fragment illegible].
Gut microbiota transplantation schedule
- First course: 27 May – 1 June, 8 capsules per day
- Second course: 27 June – 2 July, 8 capsules per day
Messages from the parent
- Passing stool used to be a big problem: very dry, all like goat droppings. Now it is once or twice a day, sometimes once, mostly banana-shaped. Now, at home or outside, she goes to the toilet by herself — she just isn't very good at wiping yet.
- She used to wet herself anywhere and could only be in nappies.
- [voice message, 17 seconds] Domi used to be unable to sit still: a lesson is 45 minutes, and it was good if she sat through some ten minutes — then she would start fidgeting. It was the same in this classroom or any other. Now she can sit through all 45 minutes.
- And the gaze matters a lot, I think.
Show the full conversation (4 more)
- At the centre there is a child with confirmed moderate autism, already 12 years old: he doesn't look at people, and whatever you say to him he looks away.
- Not confident.
- Domi also used not to look at people.
- But now she always looks very confident, her gaze is very steady.
Assessment by the centre's teacher
- Domi is in very good shape today: she follows the planned lesson sequence, has adapted well, and we worked through every task calmly and without rushing.
- In the hands-on tasks her little hands have become more dexterous, she understands instructions and carries them out, and her emotions are steadier: even when she is dissatisfied, she calms down once her attention is redirected.
- In recognising animals and facial features she has also become more interested than before, she plays along, and she is willing to handle the models and play with them for a long time.
- Imitation of actions and sounds has increased noticeably: Domi catches even small movements and copies them.
- On the whole her sitting still has progressed a great deal: about 70% of the sitting-time goal we set at the start has already been met. We keep working and look forward to even bigger surprises from Domi.
Exchange with the specialist
- The main thing is that Domi was underestimated.
- The teacher let me step out.
- I'll be back in the afternoon and will also draw up the EEG and tDCS plan for Domi.
- Mm-hm.
- Let's wait until the lesson is over and see whether she can hold out to the end.
- If anything comes up later, tell me, and say it plainly: sometimes I may not catch what you mean. Domi really is changing quite fast, and comparing her with ordinary children truly doesn't work. Domi is the fastest-progressing child I have seen. Bar none.
The parent's messages about the week
- Specialists, let me share Domi's changes over this week: she has stopped being fussy about food and has come to like vegetables; her stool is not dry and the volume is very large; her sleep is better; she sweats less and no longer wakes up. Most important of all, she is learning: a new skill every day, and today she mastered another new skill with the teacher: [fragment illegible].
- Domi is doing great!
- [fragment illegible] really wonderful. Domi's dad and I notice changes in the child every day: lately she loves imitating me, and yesterday she waved goodbye to the teacher and to her dad very attentively — her gaze no longer drifts.
- The teachers say that teaching Domi has become easy: she picks things up quickly and even builds with blocks attentively.
Caption on the food photograph: "A child who did not like any vegetables for 48 months started loving all kinds of vegetables in the 49th month."
01
Adult case
Man, age 82: depression and chronic gastrointestinal complaints
The materials describe depression, chronic diarrhea, abdominal bloating, and hair loss.
Baseline
- Long-standing diarrhea and abdominal bloating.
- Depressive symptoms.
- Hair loss was listed as an accompanying complaint.
Course timeline
Two courses
The material states that two FMT courses were completed.
After both courses
All reported outcomes refer to the period after both courses had been completed.
Changes noted afterward
- The materials report a marked reduction in diarrhea and bloating after two courses.
- The materials report a strong improvement in depressive symptoms after two courses.
- The material also shows hair regrowth over an area of about 1.5 × 2 cm and reports that previously grey hair gradually darkened.
Source: Jialan clinic presentation describing the condition before and after two courses.
Limitation: Dates, administration form, a depression scale, and concurrent treatment are not given, so the magnitude of change cannot be assessed objectively.
Below is the partner's original material in Chinese. Claims inside the image have not been independently verified and do not prove treatment effectiveness.
Translated material
A case of depression
Uncle Li, aged 82, is a patient with depression.
At the same time he developed chronic diarrhea, accompanied by abdominal bloating, hair loss (alopecia areata) and other symptoms.
After two courses of faecal microbiota transplantation, Uncle Li's diarrhea and bloating improved markedly, and his depression improved a great deal as well.
In addition, a bare patch of about 1.5 cm × 2.0 cm on the right rear of his head grew hair again, and his previously mottled grey hair gradually turned black!
The slide carries three photographs of the back of the head, labelled A, B and C. The face is not shown.
07 / 10
Seven more cases
These compact cards preserve important context without filling gaps in the source materials with assumptions.
03
Autism and ADHD
Boy, age 4
Autism, ADHD, constipation, and allergic manifestations.
What was done
An oral microbiota oil; duration is described by the number of bottles used.
What was noted
By the sixth bottle, the family noted more eye contact, answers to questions, independent expression, and daily bowel movements.
Source: Jialan clinic presentation with sequential family comments.
Limitation: There are no dates, exact dose, objective scales, or details of other therapy or training.
Below is the partner's original material in Chinese. Claims inside the image have not been independently verified and do not prove treatment effectiveness.
Translated material
A case of autism: after six bottles of oral microbiota oil, eye contact and independent expression appeared
A boy of 4, diagnosed with autism and hyperactivity disorder; no speech, no eye contact, severe food selectivity, constipation, a bowel movement every 3–4 days. Allergic to eggs, milk and the like.
The child underwent microbiota transplantation. By the sixth bottle of drops he made eye contact, began to answer questions and to express his own thoughts independently. The constipation was resolved as well — a bowel movement every day; his learning at school improved rapidly.
Conversation, 3–4 August 2021
- 3 August 2021, 11:10Tell me, what digestive symptoms does the child have: for instance, what are the bowel movements like, is there eczema or allergy, what is his mood like, is he selective about food?
- Autism, hyperactivity. He doesn't eat vegetables, the food selectivity is very severe.
- If he has milk or eggs, he gets an allergic reaction.
- Yes, this is closely connected with the gut. And what about the stool?
Show the full conversation (3 more)
- Basically once every three or four days; if we aren't careful, constipation.
- 3 August 2021, 12:00[voice message, 39 seconds]
- 4 August 2021, 13:29All right, agreed!
Voice message from the parent, 50 seconds
- We're keeping it up, and his condition lately is also all right. Going to the toilet really has become regular: occasionally there is a day or two when it works out to once every two days, but most of the time it is fine. It's summer now, so we let him try more new things — seasonal fruit. He no longer rejects it the way he used to: he can't be said to be very fond of it, but if you give it to him, you watch, you make him eat it, and he does eat it, that is, he accepts it. On the whole it's all right. But there are still some signs of hyperactivity now; next week we plan to take him here to the regional hospital, the children's hospital, to have him looked at.
Conversation after the course
- We are truly grateful that we met you this year.
- A good child, a wonderful little one 👍👍👍
- Look: today the child, who has been at kindergarten for four years, went on stage to perform for the first time.
- That really is wonderful, so moving!
- Yes, it feels as if this month's progress is visible to the naked eye.
A caption in red on the photograph of the child at a table: "4 years 2 months, no eye contact at any point" — this is the state before the course. The child's face is masked in the original.
04
Autism · early childhood
Boy, age 2½
Autism, emotional difficulties, and unformed stool.
What was done
Two courses of oil drops; the material describes use of one bottle in pipette amounts.
What was noted
The family noted calmer emotions, improved stool, and the appearance of several words.
Source: Jialan clinic presentation and family feedback included in it.
Limitation: There are no dates, standardized developmental assessment, or details of concurrent therapy.
Below is the partner's original material in Chinese. Claims inside the image have not been independently verified and do not prove treatment effectiveness.
Translated material
A case of autism: after faecal microbiota transplantation the mood improved and he became willing to talk
A boy of two and a half, Shushu (a pseudonym), diagnosed with autism: emotional problems, screaming, walking on tiptoe, no speech, unable to express his needs normally. Unformed stool, food selectivity.
After two courses of microbiota transplantation the child's emotions became stable, he is able to take part in training with his father, his stool became formed, and speech of a few words appeared.
Conversation, 29–31 October
- 29 October, 20:13The child's stool is hard today. [photograph]
- 31 October, 09:00Mm-hm.
- That is a good state.
- Has it always been like that before?
Show the full conversation (3 more)
- No, it is hard only today; most of the time it is usually loose. Also, yesterday, when I was giving the child the drops, I accidentally dropped the pipette into the bottle. Only two pipettes were taken from that bottle.
- Could you send me one more bottle next time?
- How much would that cost?
Conversation about the child's speech
- Thank you, dad. Are there big changes in the little one now?
- There is some progress.
- Wonderful 🌹
- He has become willing to repeat after the teacher.
Show the full conversation (3 more)
- Simple words.
- Good little one 👍👍👍
- He can say about ten now.
The conversation includes the photograph of the stool that the parent describes.
05
Autism · family case
Boy, age 5, and his father
Mild autism is described for the child and diarrhea for the father.
What was done
The materials state that capsules and an oil form were used together.
What was noted
The father's diarrhea was reported to stop; for the child, better social participation and less walking in circles were noted.
Source: One Jialan clinic presentation describing observations in the family.
Limitation: Two different people and outcomes are combined in one description; timing, doses, and other factors are not given.
Below is the partner's original material in Chinese. Claims inside the image have not been independently verified and do not prove treatment effectiveness.
Translated material
A case of autism: after faecal microbiota transplantation he joined the group, the spinning behaviour is gone
Male, 5 years old. Mild autism, stereotyped behaviour, likes to spin around.
After faecal microbiota transplantation the child is able to join a group quickly, and the stereotyped spinning has decreased.
A parent's first-hand account: a father and his son with mild autism underwent faecal microbiota transplantation at the same time — oral capsules and oil drops. The father's diarrhea improved, and the son became more cheerful and started approaching people himself.
Voice message from the parent, 23 seconds
- Our impression is that the speed with which the child joins a group has increased. Before, for example, when he went out to play football, it took him half a day and he found it hard to join the others; now he joins quickly. And another thing: he used to like spinning around, for example — that behaviour is gone now.
The slide shows a photograph of the child by a table; the face is not shown.
06
Autism · child
Boy, age 4
Autism, unformed stool, and allergic manifestations.
What was done
Microbiota oil drops; the exact regimen is not provided.
What was noted
The family noted changes in stool and mood, as well as in learning and imitation.
Source: Jialan clinic presentation with a brief account of the family's observations.
Limitation: There is no timeline, dose, objective measure, or information about concurrent support.
Below is the partner's original material in Chinese. Claims inside the image have not been independently verified and do not prove treatment effectiveness.
Translated material
A case of autism: after microbiota transplantation the ability to learn grew stronger and imitation improved
A 4-year-old boy: quick-tempered day to day, low initiative, unformed stool, a severely allergic constitution, and behind his peers in cognition and other areas.
After treatment with microbiota drops, the parents reported that the child's stool became formed, his temper improved, his ability to learn and take things in grew stronger, and his imitation improved.
Messages from the parent
- [video, 6 seconds]
- [video, 29 seconds]
- Thank you.
- I feel the child takes things in very quickly now.
- And imitation has become much better too.
07
Autism · child
Child from Tianjin
The materials list autism; the child's age is not provided.
What was done
Form and dose are not stated; the second course began approximately one month after the first.
What was noted
After one week, the family noted changes in sleep and behavior during sensory classes; after one month, they noted stronger attachment and social activity.
Source: Jialan clinic presentation with family messages after the first course.
Limitation: Age, course form, dose, assessment scales, and details of concurrent classes are not provided.
Below is the partner's original material in Chinese. Claims inside the image have not been independently verified and do not prove treatment effectiveness.
Translated material
Autism
Parent feedback one week after gut microbiota transplantation: the child's mother found that his sleep had improved compared with before, and there was also great progress in sensory integration classes.
Conversation one week after the course
- @Annie, hello! We finished a course, and it feels as if the child's sleep is better than before; there is progress in sensory integration, and he is doing well in class now. When I get back I'll record some sensory-integration videos for you.
- Good, let's observe carefully, the child will keep improving 🌷😊
- During this period do watch the diet: avoid spicy, very oily, fatty and sugary food as much as possible.
- Alongside that, give some apple pectin or fruit rich in pectin.
- All right, thank you. I'll keep observing and reporting back.
Parent feedback one month after gut microbiota transplantation: in the very first month the child progressed especially strongly, a clear emotional attachment appeared, he no longer plays by himself, his social qualities have grown stronger, and interaction with his parents has gradually increased. We hope that continuing transplantation treatment will bring further improvement.
Conversation one month after the course
- Hello! We are due to start the second round of transplantation on 30 July. Around what date do you send it out? 😊
- Let me report back: the most noticeable thing after the first round is that he has become very affectionate and clingy; at home he no longer plays alone and constantly asks for family to be beside him. It was not like this before.
- An emotional attachment has appeared — seize the moment and guide him into social contact, it will get better and better 🌷
- All right, thank you. About the second transplantation — is it convenient to send it this week? 😊
- Certainly, I'll arrange it.
- Thank you very much.
09
Autism · combined course
Boy, age 10
Autism, a highly restricted diet, and constipation.
What was done
Metagenomic matching, bowel cleansing, 30 ml of the oil form, probiotics, and prebiotics.
What was noted
The family noted a wider diet, less constipation, changes in sleep, and a new physical activity; emotional fluctuations were also described.
Source: Jialan clinic presentation describing a multi-part course and the family's observations.
Limitation: Several interventions were used at the same time, so changes cannot be linked to one component.
Below is the partner's original material in Chinese. Claims inside the image have not been independently verified and do not prove treatment effectiveness.
Translated material
Gut microbiota transplantation improves food selectivity and constipation in a child with autism
Miaomiao, 10 years old, male.
Autism, a monotonous diet, constipation, unwilling to engage with new things.
Intervention
- Matching: metagenomic typing
- Preparation: Shustong bowel cleansing
- Preparation used: 30 ml of gut microbiota oil
- In addition: probiotics and prebiotics
What improved
- Emotions: emotional fluctuation increased
- Diet: a richer diet than before the transplantation
- Stool and sleep: constipation improved, sleep quality increased
- New things: willing to try new climbing equipment
Conversation with health manager Jin Shuangshuang
- 13:50Hello! It's Friday again — have a lovely weekend with your family 🌹! I'd like to ask how the child is doing during the recovery period? It has turned noticeably colder since the start of winter — how is his body coping 😊?
- 14:02He is still taking prebiotics and probiotics.
- He has started eating a few more kinds of food.
- There is some fluctuation in his emotions; in class he keeps laughing out loud.
Show the full conversation (5 more)
- Good. Diversifying the diet also has to move forward steadily, only within what the child accepts and is not allergic to. And we still keep to the dietary restrictions 🍊
- I see. It may be that our new microbiota is building new metabolic pathways and producing different neurotransmitters, and this shows temporarily as a "fluctuation" or "release" of the child's emotions.
- Are there changes in anything else? For instance, stool, sleep, or everyday behaviour…
- The stool is soft, not with hard lumps as before. He sleeps from about half past ten in the evening and gets up around half past seven in the morning.
- He is willing to try the climbing equipment; before he would not go near it.
10
ADHD · October 2025
Child with ADHD
The material describes difficulty with cooperation and social interaction.
What was done
After hospital admission, the child received intravenous immunoglobulin for four days, then began microbiota capsules on 28 September.
What was noted
The parent noted better cooperation and communication. NSE changed from 19.19 to 16.8, while the stated reference limit was no higher than 16.3.
Source: Jialan clinical material from October 2025 with a parent message and two NSE values.
Limitation: Capsules began after another treatment, and the repeat NSE value remained above the stated range; the changes cannot be attributed to the capsules.
Below is the partner's original material in Chinese. Claims inside the image have not been independently verified and do not prove treatment effectiveness.
Translated material
Gut microbiota transplantation as an intervention for ADHD
- Before transplantation
- 22 September
- After transplantation
- 22 October (first course)
Before transplantation, 22 September
- No toys.
- Cooperation and social contact.
- Today is the 22nd.
- On 20 September he was admitted to hospital and had four days of immunoglobulin infusions; on 28 September he started taking the microbiota.
After the first course, 22 October
- The key word is cooperation.
- There have been no complaints these days either.
- These past evenings, when we do homework and I get a little impatient, he suddenly gives me a smile instead of pushing back.
- I say to him: you're grinning at me, but I'm glad, because you don't raise a hand to someone who is smiling — now I don't know what to do, what am I to do?
Show the full conversation (6 more)
- And then he smiles back at me.
- Then I talked with him: this is a matter of attitude to learning. And he actually heard me out, and then started on his homework.
- I now have the feeling that he can be "started up": talking to him is not such hard work any more. Before, he could not understand, could not carry things out — only opposition.
- At lunch we went out to eat and he told me very happily: "Mum, do you know who I played with in PE? Dora. We played a game, I'll teach you." And then he played it with me: the two of us against each other, one on one, with winning and losing, and someone gets killed. He was killed — and he did not cry or lose his temper at all. I asked why he had never played this with me before; he said: before I couldn't play it, and I couldn't play together with them either, I only learned it from them yesterday.
- Key words: before, he couldn't play together with them.
- Isn't that socialising? My goodness, there is social contact now.
Test before the course
| Indicator | NSE, neuron-specific enolase |
|---|---|
| Result | 19.19 ↑ |
| Reference value | 0–16.3 ng/ml |
Laboratory form after the first course
| Indicator | Neuron-specific enolase |
|---|---|
| Result | 16.8 ↑ |
| Reference range | ≤ 16.3 ng/ml |
| Sample type | blood |
| Requesting doctor | You Xin |
| Reviewing doctor | Zhang Fang |
| Request date | 14 October 2025, 15:13:50 |
| Sample received | 19 October 2025, 12:31:58 |
| Review date | 20 October 2025, 12:47:39 |
Notes on the form: "Sample verified, no haemolysis" and "This report is for reference only; the paper report printed by the hospital is authoritative".
The parent's comment on the test
- On the day of admission this indicator was 19.19; after four days of treatment and then almost half a month more of taking the faecal microbiota capsules…
- 20 September and 19 October.
- One month.
- This indicator has come down.
- Yes, the brain [fragment illegible]
How to read these stories
What case stories cannot prove
A patient story can provide context, but it cannot replace a clinical study or an individual medical assessment.
They do not promise the same outcome
Age, diagnoses, diet, concurrent treatment, and baseline condition differ from person to person.
They do not establish a cause
A change occurring after a course does not, by itself, prove that the course caused it.
They do not replace a control group
These materials do not compare participants with people who did not receive the intervention.
They do not replace a consultation
An appropriate format, possible risks, and realistic goals must be discussed for the individual situation.
What appears in the materials
Forms and intervals varied
These details describe only the published cases and do not form a universal course regimen.
Capsules
One detailed case states two six-day courses of eight capsules per day; other stories do not provide a complete regimen.
Oil form and drops
The materials mention an oil form, drops, and use alongside capsules; one case states a volume of 30 ml.
Repeat courses
In two stories, a second course began approximately one month later, but these examples cannot establish a general interval.
Discuss your situation
Cases provide context; a decision requires assessment
A consultation can cover baseline information, goals, and limitations—without promising to reproduce someone else's outcome.